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Triage for management of cervical high-grade squamous intraepithelial lesion patients with positive margin

null

《医学前沿（英文）》 2017年 第11卷 第2期   页码 223-228 doi: 10.1007/s11684-017-0517-8

摘要：

The objective of this study is to guide a triage for the management of cervical high-grade squamous intraepithelial lesion (HSIL) patients with positive margin by conization. Clinico-pathological data of HSIL patients with positive margin by conization were retrospectively collected from January 2009 to December 2014. All patients underwent secondary conization or hysterectomy within 6 months. The rate of residual lesion was calculated, and the factors associated with residual lesion were analyzed by univariate and multivariate analyses. Among a total of 119 patients, 56 (47.06%) patients presented residual HSIL in their subsequent surgical specimens, including 4 cases of invasive cervical carcinoma (3 stage IA1 and 1 stage IA2 patients). Univariate analysis showed that patient age>35 years (P=0.005), menopausal period>5 years (P=0.0035), and multiple-quadrant involvement (P=0.001) were significantly correlated with residual disease; however, multivariate analysis revealed that multiple-quadrant involvement (P=0.001; OR, 3.701; 95%CI, 1.496–9.154) was an independent risk factor for residual disease. Nearly half of HSIL patients with positive margin by conization were disease-free in subsequent surgical specimens, and those with multiple positive margins may consider re-conization or re-assessment.

关键词： cervical high-grade squamous intraepithelial lesion     conization     positive surgical margin     hysterectomy    

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Development of a novel hand−eye calibration for intuitive control of minimally invasive surgical robot

《机械工程前沿（英文）》 2022年 第17卷 第3期 doi: 10.1007/s11465-022-0698-y

摘要： Robotic-assisted surgical system has introduced a powerful platform through dexterous instrument and hand−eye coordination intuitive control. The knowledge of laparoscopic vision is a crucial piece of information for robot-assisted minimally invasive surgery focusing on improved surgical outcomes. Obtaining the transformation with respect to the laparoscope and robot slave arm frames using hand−eye calibration is essential, which is a key component for developing intuitive control algorithm. We proposed a novel two-step modified dual quaternion for hand−eye calibration in this study. The dual quaternion was exploited to solve the hand−eye calibration simultaneously and powered by an iteratively separate solution. The obtained hand−eye calibration result was applied to the intuitive control by using the hand−eye coordination criterion. Promising simulations and experimental studies were conducted to evaluate the proposed method on our surgical robot system. We extensively compared the proposed method with state-of-the-art methods. Results demonstrate this method can improve the calibration accuracy. The effectiveness of the intuitive control algorithm was quantitatively evaluated, and an improved hand−eye calibration method was developed. The relationship between laparoscope and robot kinematics can be established for intuitive control.

关键词： minimally invasive surgery     hand−eye calibration     intuitive control     surgical robot     dual quaternion    

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Fault classification and reconfiguration of distribution systems using equivalent capacity margin method

K. Sathish KUMAR, T. JAYABARATHI

《能源前沿（英文）》 2012年 第6卷 第4期   页码 394-402 doi: 10.1007/s11708-012-0211-0

摘要： This paper investigates the capability of support vector machines (SVM) for prediction of fault classification and the use of the concept of equivalent capacity margin (ECM) for restoration of the power system. The SVM, as a novel type of machine learning based on statistical learning theory, achieves good generalization ability by adopting a structural risk minimization (SRM) induction principle aimed at minimizing a bound on the generalization error of a model rather than the minimization of the error on the training data only. Here, the SVM has been used as a classification. The inputs of the SVM model are power and voltage values. An equation has been developed for the prediction of the fault in the power system based on the developed SVM model. The next steps of this paper are the restoration and reconfiguration by using the ECM concept, the development of a code, and the testing of the results with various load outages, which have been executed for a 12 load system.

关键词： support vector machines (SVM)     structural risk minimization (SRM)     equivalent capacity margin (ECM)     restoration     fault classification    

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Cutting performance of surgical electrodes by constructing bionic microstriped structures

《机械工程前沿（英文）》 2023年 第18卷 第1期 doi: 10.1007/s11465-022-0728-9

摘要： Surgical electrodes rely on thermal effect of high-frequency current and are a widely used medical tool for cutting and coagulating biological tissue. However, tissue adhesion on the electrode surface and thermal injury to adjacent tissue are serious problems in surgery that can affect cutting performance. A bionic microstriped structure mimicking a banana leaf was constructed on the electrode via nanosecond laser surface texturing, followed by silanization treatment, to enhance lyophobicity. The effect of initial, simple grid-textured, and bionic electrodes with different wettabilities on tissue adhesion and thermal injury were investigated using horizontal and vertical cutting modes. Results showed that the bionic electrode with high lyophobicity can effectively reduce tissue adhesion mass and thermal injury depth/area compared with the initial electrode. The formation mechanism of adhered tissue was discussed in terms of morphological features, and the potential mechanism for antiadhesion and heat dissipation of the bionic electrode was revealed. Furthermore, we evaluated the influence of groove depth on tissue adhesion and thermal injury and then verified the antiadhesion stability of the bionic electrode. This study demonstrates a promising approach for improving the cutting performance of surgical electrodes.

关键词： surgical electrodes     tissue adhesion     thermal injury     bionic structures     cutting performance     medical tools    

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Comparison of surgical indications for hysterectomy by age and approach in 4653 Chinese women

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《医学前沿（英文）》 2014年 第8卷 第4期   页码 464-470 doi: 10.1007/s11684-014-0338-y

摘要：

Approximately one million hysterectomies are performed each year in China. However, national data regarding the indications and the surgical approaches for hysterectomy are lacking. The aim of this study was to examine the surgical indications for hysterectomy in different age groups and the relative merits of different surgical approaches for hysterectomy in Chinese women. Clinical data from 4653 cases of hysterectomy performed in Tongji Hospital from 2004 to 2009 were analysed. Hysterectomy was most commonly performed among women aged 40--49 years (2299; 49.4%). Overall, colporrhagia and abdominal pain were the two most common indications for hysterectomy. The most common indications by age groups were as follows: malignant ovarian tumour,<20 years; malignant uterine tumour, 20--29 and 30--39 years; uterine myoma, 40--49 and 50--59 years; and uterine prolapse, 60--69 and>70 years. The proportion of malignant aetiology also varied by age, being the highest in women aged<20 years (75.0%) and the lowest in those aged 40--49 years (19.9%). Approximately 35% women who had hysterectomies also had concomitant bilateral oophorectomy. The lowest rate of oophorectomy occurred in women aged 30--39 years (15.8%), whereas the highest rate was in those aged 50--59 years (75.9%). The abdominal surgical approach was used in 84% of all hysterectomies. Surgeries using the vaginal approach required a significantly shorter operating time (118 min average) than all other approaches (P<0.05). Both the amount of bleeding and the blood transfusion volume required were smaller in vaginal approaches, with no significant differences between the others. The surgical approaches used were also related to the scope of surgery. Both the surgical indications and the rates of bilateral oophorectomy varied by age. In terms of both operating time and the amount of bleeding and blood transfusion volume required, the vaginal approach was superior to all other surgical approaches.

关键词： hysterectomy     surgical indications     surgical approach     bilateral oophorectomy    

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Potential indicators predict progress after surgical resection of gastrointestinal stromal tumors

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《医学前沿（英文）》 2012年 第6卷 第3期   页码 317-321 doi: 10.1007/s11684-012-0203-9

摘要：

In order to find out the potential indicators predicting prognosis of malignant gastrointestinal stromal tumors (GISTs) after surgical resection, we collected clinical records of 80 patients with malignant GISTs. Tumor location, size, mitotic index, necrosis were compared with the prognosis of malignant GISTs by Kaplan-Meier method and log-rank test. After a median follow-up of 844 days (52–2 145), we found that as National Institutes of Health suggested, tumors with intermediate risk had more favorable prognosis than that with high risk. Their 3-year survival rate were 65.3% and 41.3%, respectively (P<0.001). Moreover, tumor size and mitotic index were associated with free survival. The 3-year survival rate for patients with tumor size≤10 cm and>10 cm were 62.3% and 41.8%, respectively (P = 0.002), Tumors with mitotic index≤5/50 HPF had a higher 3-year survival rate than tumors with mitotic index>5/50 HPF (67.1% versus 40.7%, P = 0.005). The presence of necrosis was directly related to the malignant behavior. The 3-year survival rate for presence and absence necrosis were 50.8% and 64.8% (P = 0.008). From the present study, we can conclude that besides tumors size and mitotic index, tumor location and necrosis also influence on the long-term survival of patient with malignant GISTs after surgical resection.

关键词： gastrointestinal stromal tumors     surgery     survival    

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State-of-the-art of intelligent minimally invasive surgical robots

Masakatsu G. Fujie, Bo Zhang

《医学前沿（英文）》 2020年 第14卷 第4期   页码 404-416 doi: 10.1007/s11684-020-0743-3

摘要： A number of developed countries are rapidly turning into super-aged societies. Consequently, the demand for reduced surgical invasiveness and enhanced efficiency in the medical field has increased due to the need to reduce the physical burden on older patients and shorten their recovery period. Intelligent surgical robot systems offer high precision, high safety, and reduced invasiveness. This paper presents a review of current intelligent surgical robot systems. The history of robots and three types of intelligent surgical robots are discussed. The problems with current surgical robot systems are then analyzed. Several aspects that should be considered in designing new surgical systems are discussed in detail. The paper ends with a summary of the work and a discussion of future prospects for surgical robot development.

关键词： robot history     medical robot     surgical robot     radiofrequency ablation     organ model    

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Advances in the management of the surgical complications for congenital cataract

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《医学前沿（英文）》 2012年 第6卷 第4期   页码 360-365 doi: 10.1007/s11684-012-0235-1

摘要：

The greatest concern in children with cataracts is irreversible visual loss. The timing of congenital cataract surgery is critical for the visual rehabilitation. Cataract surgery in children remains complex and challenging. The incidence of complications during or after operation is higher in children than adults. Some complications could be avoided by meticulous attention to surgical technique and postoperative care, and others were caused by more exuberant inflammatory response associated with surgery on an immature eye or the intrinsic eyes abnormalities. Utilizing of advanced techniques and timely applying topical corticosteroids and cycloplegic agents can reduce the occurrence of visual axis opacification. Operation on children with strabismus or nystagmus, and applying occlusion therapy on amblyopic eyes can balance the visual inputs to the two eyes. Diagnosis of glaucoma following congenital cataract surgery requires lifelong surveillance and continuous assessment of the problem. So cataract surgeries in children are not the end of journey, but one step on the long road to visual rehabilitation. This paper describes recent evidence from the literature regarding the advance of management after congenital cataract surgery.

关键词： cataract/congenital     surgery     cataract/complication    

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Review of surgical robotic systems for keyhole and endoscopic procedures: state of the art and perspectives

Yuyang Chen, Shu’an Zhang, Zhonghao Wu, Bo Yang, Qingquan Luo, Kai Xu

《医学前沿（英文）》 2020年 第14卷 第4期   页码 382-403 doi: 10.1007/s11684-020-0781-x

摘要： Minimally invasive surgery, including laparoscopic and thoracoscopic procedures, benefits patients in terms of improved postoperative outcomes and short recovery time. The challenges in hand–eye coordination and manipulation dexterity during the aforementioned procedures have inspired an enormous wave of developments on surgical robotic systems to assist keyhole and endoscopic procedures in the past decades. This paper presents a systematic review of the state-of-the-art systems, picturing a detailed landscape of the system configurations, actuation schemes, and control approaches of the existing surgical robotic systems for keyhole and endoscopic procedures. The development challenges and future perspectives are discussed in depth to point out the need for new enabling technologies and inspire future researches.

关键词： surgical robots     keyhole surgery     endoscopic surgery    

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准西海相浅层石炭系火山凝灰岩油气发现的意义

王建勇,王学忠,马立群

《中国工程科学》 2012年 第14卷 第7期   页码 81-86

摘要：

2011年，准西海相浅层石炭系火山凝灰岩油气勘探取得了突破，见到了良好的油气显示，特别是排61井在855.7～949.6 m井段，常规试油获得日产6 t的工业油流，50 ℃地面脱气原油黏度为390 mPa·s。排61地区石炭系稳定的海相沉积层既是深部油源岩，又是优质储集层。岩浆活动提供了火山岩储层发育和分布的基础。火山凝灰岩经受了强烈的风化作用和有机酸溶蚀作用，风化壳及次生裂缝很发育，成为优质储层。深部二叠系油气沿红车断裂带和地层超剥带不整合面向高部位运聚成藏。二叠系和三叠系致密的火山岩或泥岩沉积覆盖作为区域性盖层对石炭系油气后期保存至关重要。针对石炭系储层成像较差的难题发展了地震叠前时间偏移处理技术，火山岩地震和测井响应特征比较明显，应用成像测井和核磁共振技术实现了裂缝的定性识别和定量描述。

关键词： 石炭系     火山凝灰岩     海相沉积     浅层     准噶尔盆地西缘    

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NO conversion by positive streamer discharge—effects of gas compositions and reaction conditions

HE Wei, ZHU Tianle, LI Jing

《环境科学与工程前沿（英文）》 2007年 第1卷 第2期   页码 153-158 doi: 10.1007/s11783-007-0027-z

摘要： The effects of gas compositions and reaction conditions on NO conversion by positive streamer discharge were experimentally investigated by using a link tooth wheel-cylinder reactor. The results showed that NO conversion increased w

关键词： conversion     streamer discharge     wheel-cylinder     positive streamer    

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基于最大间隔的贝叶斯分类器 Article

Tao-cheng HU,Jin-hui YU

《信息与电子工程前沿（英文）》 2016年 第17卷 第10期   页码 973-981 doi: 10.1631/FITEE.1601078

摘要： 概要：多分类学习中经常需要考虑在泛化性能和计算开销间进行权衡。本文提出一个生成式概率多分类器，综合考虑了泛化性和学习/预测速率。我们首先证明了我们的分类器具有最大间隔性质，这意味着对于未来数据的预测精度几乎和训练阶段一样高。此外，我们消除了目标函数中的大量的局部变元，极大地简化了优化问题。通过凸分析和概率语义分析，我们设计了高效的在线算法，与经典情形的最大不同在于这个算法使用聚集而非平均化处理梯度。实验证明了我们的算法具有很好的泛化性能和收敛速度。

关键词： 多类学习；最大间隔学习；在线算法    

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Prevention of surgical site infection under different ventilation systems in operating room environment

Zhijian Liu, Haiyang Liu, Hang Yin, Rui Rong, Guoqing Cao, Qihong Deng

《环境科学与工程前沿（英文）》 2021年 第15卷 第3期 doi: 10.1007/s11783-020-1327-9

摘要： Abstract • The effectiveness of four different ventilation systems was compared in depth. • Airflow and bacteria-carrying particles concentration were quantitatively analyzed. • Vertical laminar airflow with high airflow rate could not achieve desired effect. • Temperature-controlled airflow ventilation could guarantee air cleanliness. Biological particles in the operating room (OR) air environment can cause surgical site infections (SSIs). Various ventilation systems have been employed in ORs to ensure an ultraclean environment. However, the effect of different ventilation systems on the control of bacteria-carrying particles (BCPs) released from the surgical staff during surgery is unclear. In this study, the performance of four different ventilation systems (vertical laminar airflow ventilation (VLAF), horizontal laminar airflow ventilation (HLAF), differential vertical airflow ventilation (DVAF), and temperature-controlled airflow ventilation (TAF)) used in an OR was evaluated and compared based on the spatial BCP concentration. The airflow field in the OR was solved by the Renormalization Group (RNG) k-e turbulence model, and the BCP phase was calculated by Lagrangian particle tracking (LPT) and the discrete random walk (DRW) model. It was found that the TAF system was the most effective ventilation system among the four ventilation systems for ensuring air cleanliness in the operating area. This study also indicated that air cleanliness in the operating area depended not only on the airflow rate of the ventilation system but also on the airflow distribution, which was greatly affected by obstacles such as surgical lamps and surgical staff.

关键词： Operating room (OR)     Bacteria-carrying particles (BCPs)     Surgical site infections (SSIs)     Ventilation    

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把握生物经济时代精神，实践进步的幸福观

甘自恒

《中国工程科学》 2007年 第9卷 第2期   页码 5-11

摘要：

据预测，2020年，全球将进入以生物技术产业为主导产业的生物经济时代；阐述了生物经济的提出、 分类、特征和定义；主张把握生物经济时代精神，实践进步的幸福观；探讨了为什么要强调谋求人民幸福，什 么是进步的幸福观，应提倡那些进步的幸福观，以及我国科技界应该怎样实践进步的幸福观。

关键词： 生物经济     幸福     进步的幸福观    

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Identification of surgical patients at high risk of OSAS using the Berlin Questionnaire to detect potential

null

《医学前沿（英文）》 2018年 第12卷 第2期   页码 189-195 doi: 10.1007/s11684-017-0533-8

摘要：

Obstructive sleep apnea syndrome (OSAS) increases the risk of post-surgery complications. This study uses Berlin Questionnaire (BQ) to identify Chinese adult surgical patients who are at a high risk of OSAS and to determine if the BQ could be used to detect potential high risk of adverse respiratory events in the post anesthesia care unit (PACU). Results indicated that only 11.4% of the patients were considered at a high risk of OSAS. Age and body mass index are the key factors for the risk of OSAS prevalence in China and also gender specific. Furthermore, the incidence of adverse respiratory events in the PACU was higher in patients with high risk of OSAS than others (6.8% vs. 0.9%, <0.001). They also stayed longer than others in the PACU (95±28 min vs. 62±19 min, <0.001). Age, high risk for OSAS, and smoking were independent risk factors for the occurrence of adverse respiratory events in the PACU. The BQ may be adopted as a screening tool for anesthesiologists in China to identify patients who are at high risk of OSAS and determine the potential risk of developing postoperative respiratory complications in the PACU.

关键词： obstructive sleep apnea     Berlin Questionnaire     Chinese surgical patients     adverse respiratory event    

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标题 作者 时间 类型 操作

Triage for management of cervical high-grade squamous intraepithelial lesion patients with positive margin

null

期刊论文

Development of a novel hand−eye calibration for intuitive control of minimally invasive surgical robot

期刊论文

Fault classification and reconfiguration of distribution systems using equivalent capacity margin method

K. Sathish KUMAR, T. JAYABARATHI

期刊论文

Cutting performance of surgical electrodes by constructing bionic microstriped structures

期刊论文

Comparison of surgical indications for hysterectomy by age and approach in 4653 Chinese women

null

期刊论文

Potential indicators predict progress after surgical resection of gastrointestinal stromal tumors

null

期刊论文

State-of-the-art of intelligent minimally invasive surgical robots

Masakatsu G. Fujie, Bo Zhang

期刊论文

Advances in the management of the surgical complications for congenital cataract

null

期刊论文

Review of surgical robotic systems for keyhole and endoscopic procedures: state of the art and perspectives

Yuyang Chen, Shu’an Zhang, Zhonghao Wu, Bo Yang, Qingquan Luo, Kai Xu

期刊论文

准西海相浅层石炭系火山凝灰岩油气发现的意义

王建勇,王学忠,马立群

期刊论文

NO conversion by positive streamer discharge—effects of gas compositions and reaction conditions

HE Wei, ZHU Tianle, LI Jing

期刊论文

基于最大间隔的贝叶斯分类器

Tao-cheng HU,Jin-hui YU

期刊论文

Prevention of surgical site infection under different ventilation systems in operating room environment

Zhijian Liu, Haiyang Liu, Hang Yin, Rui Rong, Guoqing Cao, Qihong Deng

期刊论文

把握生物经济时代精神，实践进步的幸福观

甘自恒

期刊论文

Identification of surgical patients at high risk of OSAS using the Berlin Questionnaire to detect potential

null

期刊论文